GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9894429 | 1 | rs3935543 | chr17:79579874 | TSPAN10 | chr17:79609349-79615778:+ | 0.63 | 6.68 | 1.61E-9 | Eye color traits |
| THYM | cis | rs9457247 | 1 | rs393558 | chr6:167397750 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs393727 | chr6:167398632 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs394522 | chr6:167398071 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs2028299 | 1 | rs3960018 | chr15:90383307 | AP3S2 | chr15:90373832-90456222:- | -0.43 | -4.89 | 4.09E-6 | Type 2 diabetes |
| THYM | cis | rs9457247 | 1 | rs397713 | chr6:167386714 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs398278 | chr6:167388169 | RNASET2 | chr6:167343008-167412795:- | -0.45 | -7.53 | 2.89E-11 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs400063 | chr6:167386592 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs400176 | chr6:167406238 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs400837 | chr6:167411008 | RNASET2 | chr6:167343008-167412795:- | -0.46 | -7.49 | 3.6E-11 | Crohn's disease |
| THYM | cis | rs2243480 | 1 | rs402418 | chr7:65509469 | CCT6P1 | chr7:65216092-65228661:+ | 0.67 | 5.68 | 1.48E-7 | Diabetic kidney disease |
| THYM | cis | rs9457247 | 1 | rs402749 | chr6:167386104 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs404222 | chr6:167402150 | RNASET2 | chr6:167343008-167412795:- | -0.45 | -7.53 | 2.89E-11 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs405553 | chr6:167395058 | RNASET2 | chr6:167343008-167412795:- | -0.47 | -7.83 | 7.0E-12 | Crohn's disease |
| THYM | cis | rs9457247 | 1 | rs406095 | chr6:167409087 | RNASET2 | chr6:167343008-167412795:- | -0.46 | -7.49 | 3.6E-11 | Crohn's disease |